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Topic

Hair structure, from follicle to fiber

The hair you see is dead, hardened keratin made of three layers, which is why care is about protecting it rather than repairing it.

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A hair has up to three layers. The cuticle is the thin protective shell (about 10% of the weight). The cortex gives strength (86 to 90%). A medulla core is present in some hairs only. Plowman 2018 ↗ Wagner 2007 ↗
Two microscope-style illustrations side by side. Left: a hair strand whose cuticle scales lie flat and smooth. Right: a damaged strand with chipped, lifted scales and a frayed split end.
Illustration in the style of an electron microscope picture (AI-generated, not a real micrograph). Left, healthy cuticle. Right, worn cuticle and a split end. Bleaching breaks cuticle into small pieces, and splits can start inside the fibre. Kizawa 2005 ↗ Taylor 2024 ↗

Key takeaways

  • A hair fiber has up to three layers: an outer cuticle (overlapping dead cells, about 10% of the weight), a central cortex (86-90% of the weight, where the strength is) and sometimes a medulla, a hollow or loosely packed core that is more common in thicker fibers Plowman 2018.
  • The cuticle is the face your hair shows the world. Its scales control shine, friction, tangling and how water gets in. It wears away first. In hair longer than 2.4 m, the cuticle wore away progressively over roughly the first metre before the cortex was affected Thibaut 2010.
  • One fatty acid, 18-methyleicosanoic acid (18-MEA), is bonded to the outside of cuticle cells and makes the fiber water-repelling. Removing it makes the fiber water-loving, and alkaline treatments are reported to strip it Jones and Rivett 1997.
  • The cortex is a composite of stiff keratin filaments in a softer protein matrix. Cross-linking in the matrix keeps the filaments stiff even when wet Greenberg and Fudge 2013.
  • The join between cuticle and cortex is a weak point. In stress tests of curly hair from one donor, cracks started there and merged until the fiber snapped, at unpredictable places Camacho-Bragado 2015.
  • Breakage is usually cumulative: grooming and environmental stress add up as internal cracks. Gentle handling every day matters more than one rescue product.
  • Inner fine structure is nearly identical between people. In 12 people, including twins, X-ray diffraction found the same keratin and lipid signals; only some extra lipid signals differed, and those ran in families Yang 2014.

The follicle makes the fiber

Hair is produced in the follicle bulb and hardens as it rises; by the time it emerges, the cells are dead. The shape of the follicle sets the curve of the fiber (see curl pattern), and the growth cycle is covered in the hair growth cycle. Nothing you apply changes what the follicle already made. Products only change what happens to that fiber afterward, so "repair" claims really mean coating, filling or cross-linking a fixed structure.

Layer by layer

Layer Share of fiber What it is Why it matters
Cuticle About 10% by weight Flat dead cells overlapping like roof tiles, pointing root to tip, with a thin lipid layer on the outside Shine, friction, tangling, water uptake. First to wear, lift or chip
Cortex 86-90% Spindle-shaped cells packed with keratin filaments in a protein matrix Strength, stretch and curl. Damage here (bleach, very high heat) is the serious kind
Medulla Variable A central column of spaces with air-filled granules No clear effect on strength; medullated and non-medullated fibers had similar average mechanical properties, but medullated ones were less uniform Wagner and Joekes 2007
Cell membrane complex Very small Lipid and protein glue between cells Holds scales and cortex cells together; where cracks spread

Bonds that hold keratin together

  • Hydrogen bonds are weak and numerous. Water disrupts the protein-protein ones, which is why hair set wet and dried holds its shape until it gets wet again Harland 2022.
  • Disulfide bonds are strong and permanent. Perms, relaxers and bleach act on them. Under tension some break first near the protein ends, and this differs between wet and dry fibers (a sheep wool study, not human hair) Harland 2022.

Water and the fiber

Hair absorbs water and swells. In a tensile study of bleached and unbleached hair given heat treatments, wet-state stiffness (modulus) was judged the best single measure of damage from chemical and physical treatments Wortmann 2022. Calcium and magnesium from hard water build up in the cuticle, more so in chemically damaged hair, and stiffen the fiber. Style retention improved in virgin hair but dropped slightly in bleached hair Evans 2011 (industry-affiliated authors).

How hair ages from root to tip

In very long virgin hair, the cuticle wore away over about the first metre while the cortex stayed intact. Further along, scale damage was significant and lined up with falling ceramide and 18-MEA levels. Most mechanical and optical properties then decayed Thibaut 2010 (industry-funded). This is why ends look and feel worse than roots even without styling damage, and why trimming is the only true fix for old ends.

Lipids

A 2023 systematic review of 59 papers found that hair lipid composition varies by ancestry-linked hair type and by layer, and that lipid loss is accelerated by bleach, dye, perms, straightening, surfactants, sun and aging, leading to dehydrated, breakable, dull hair Csuka 2023. Lab studies on African hair found more, and more disordered, cuticle lipids and faster water diffusion Marti 2016, Oliver 2020, Barba 2022. Between Caucasian, Asian and African samples no difference in inner fiber structure was found, while geometry, mechanics and water swelling did differ Franbourg 2003. More in hair by ancestry.

What it means for your hair

  • Curl pattern: bends concentrate stress. See curl pattern and brushing and detangling.
  • Strand thickness: coarse fibers are more likely to have a medulla. See strand thickness.
  • Porosity: in practice a marker of cuticle and lipid-layer damage. See hair porosity.
  • Length: longer hair has had more exposure. Assume ends older than a couple of years are cuticle-worn.

Myths and facts

  • "Hair can be repaired." Largely false, because the fiber is dead. Products can smooth, coat or add temporary cross-links; see bond builders.
  • "Curly hair is a different kind of keratin." Not supported at the nanoscale Franbourg 2003, Yang 2014. Geometry and surface lipids differ.
  • "Breakage is one bad event." More often it is cumulative internal cracking Camacho-Bragado 2015.

Practical points

  1. Treat the ends as the oldest, most worn part of the fiber. Expect them to need more conditioning and eventual trimming.
  2. Keep wet-hair mechanical stress low: detangle gently with conditioner slip.
  3. Avoid stacking chemical and heat damage. They add up.
  4. Be skeptical of any "rebuilds the cortex from the outside" claim that shows no penetration and strength data.
  5. If hair breaks near the scalp or comes out with a white bulb, think shedding or scalp rather than fiber damage.

Bottom line

Hair is dead keratin: protect it, don't expect to repair it. The cuticle wears first, breakage accumulates, and the ends are always the oldest part. Inner structure is much the same across people; what differs is shape, surface lipids and history of treatment. Several of the key studies are small or industry-funded, so treat the details as a good working model rather than settled fact.

Studies 15

Plowman JE, Harland DP. Fibre Ultrastructure. Adv Exp Med Biol. 2018

Design
review

Result: The cuticle is about 10% of fiber weight and the cortex 86-90%; a medulla is more common as fibers get thicker.

Read the study ↗

Yang FC, Zhang Y, Rheinstadter MC. The structure of people's hair. PeerJ. 2014

Design
other
People
12

Result: X-ray diffraction found the same keratin and lipid signals in all people studied; only some extra lipid signals differed, and these ran in families.

Read the study ↗

Jones LN, Rivett DE. The role of 18-methyleicosanoic acid in the structure and formation of mammalian hair fibres. Micron. 1997

Design
review

Result: 18-methyleicosanoic acid is bonded to the outside of cuticle cells and makes hair water-repellent; alkaline treatments strip it, leaving a water-attracting surface.

Read the study ↗

Thibaut S et al. Chronological ageing of human hair keratin fibres. Int J Cosmet Sci. 2010

Design
other

Result: In hair longer than 2.4 m the cuticle wore away over roughly the first metre; further out, scale damage lined up with falling ceramide and 18-MEA levels and mechanical properties decayed.

Read the study ↗

Greenberg DA, Fudge DS. Regulation of hard alpha-keratin mechanics via control of intermediate filament hydration: matrix squeeze revisited. Proc Biol Sci. 2013

Design
other

Result: Cross-linking in the protein matrix keeps keratin filaments stiff even when the hair is wet.

Read the study ↗

Harland DP et al. The susceptibility of disulfide bonds to modification in keratin fibers undergoing tensile stress. Biophys J. 2022

Design
other

Result: Water disrupts protein hydrogen bonds, and under tension some disulfide bonds break first near the protein ends, differently wet and dry (sheep wool, not human hair).

Read the study ↗
Show 9 more studies

Camacho-Bragado GA, et al. Understanding breakage in curly hair. Br J Dermatol. 2015

Design
other
People
1

Result: In curly hair from one donor, cracks started at the cuticle-cortex junction and grew under grooming stress until the fiber snapped; a 2005 survey found 96% of African-American women reported breakage.

Read the study ↗

Wagner R, Joekes I. Hair medulla morphology and mechanical properties. J Cosmet Sci. 2007

Design
other

Result: Medullated and non-medullated fibers had similar average mechanical properties, but medullated fibers were less uniform.

Read the study ↗

Franbourg A et al. Current research on ethnic hair. J Am Acad Dermatol. 2003

Design
review

Result: No difference in the fine structure of Caucasian, Asian and African fibers, while geometry, mechanics and water swelling differed.

Read the study ↗

Wortmann FJ, Quadflieg JM, Wortmann G. Comparing hair tensile testing in the wet and the dry state. Int J Cosmet Sci. 2022

Design
other

Result: In untreated hair, wet modulus was 1.89 GPa vs 3.95 GPa dry (about half), wet break stress 191 vs 229 MPa and wet break extension 57.5% vs 46.9%; twice-bleached hair was weaker still when wet (167 MPa, 1.63 GPa). About 30 fibres per tress, 16 tresses, one hair batch, lab study, one co-author at an industry institute. Wet modulus was the best single damage measure and dry break stress a feasible alternative.

Read the study ↗

Evans AO, Marsh JM, Wickett RR. The structural implications of water hardness metal uptake by human hair. Int J Cosmet Sci. 2011

Design
other

Result: Calcium and magnesium from hard water concentrate in the cuticle, more in chemically damaged hair, and stiffen the fiber; style retention improved in virgin hair but dropped slightly in bleached hair.

Read the study ↗

Csuka DA et al. A systematic review on the lipid composition of human hair. Int J Dermatol. 2023

Design
systematic review
People
59

Result: Hair lipid composition varies by hair type and layer, and lipid loss is accelerated by bleach, dye, perms, straightening, surfactants, sun and aging.

Read the study ↗

Marti M et al. The influence of hair lipids in ethnic hair properties. Int J Cosmet Sci. 2016

Design
other

Result: African hair had more, and more disordered, cuticle lipids and higher water permeability; removing apolar lipids reduced permeability and raised strength in the African fibers tested.

Read the study ↗

Oliver MA et al. Ethnic hair: thermoanalytical and spectroscopic differences. Skin Res Technol. 2020

Design
other

Result: East Asian hair resisted hydration changes most and had very low cuticle lipids, European hair took up the most water, and African hair had the fastest water diffusion.

Read the study ↗

Barba C et al. Lipid distribution on ethnic hairs by FTIR synchrotron spectroscopy. Skin Res Technol. 2022

Design
other

Result: Lipid distribution differed between Asian, African and Caucasian hair, with more disordered cuticle lipids in African hair.

Read the study ↗