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Encyclopedia · surfactant

Sodium cocoyl glutamate

An amino-acid-based cleanser that was among the best-tolerated surfactants in a 105-patient patch-test study, with no scalp or hair trials yet.

Cosmetic ingredient Cost $ Safety: minor

drynessdry scalpitchy scalppoor curl definition

What it is

Sodium cocoyl glutamate is formed from coconut fatty acids and glutamic acid. It is a mild anionic with gentle foam, used in sulfate-free shampoos and facial cleansers.

How it works

It forms anionic micelles with low skin interaction. Mixed with SLS, it reduced SLS irritation in volunteers, although that study used the related sodium lauroyl glutamate (Lee 1994).

What the studies show

  • In 105 patients patch-tested with eight cleansing surfactants, none caused irritation or allergic reactions at the tested dilution. The best tolerated were sodium cocoyl glutamate, sodium lauroyl oat amino acids and disodium cocoamphodiacetate, while cocamidopropyl betaine from the standard series gave 5 positives (Corazza 2010).
  • In 15 volunteers with randomized skin sites, a glutamate surfactant was much less irritating than SLS, and mixing it with SLS reduced SLS irritation (Lee 1994).
  • A review gives an overview of shampoo surfactant raw materials and the trend toward sulfate-free systems (Cornwell 2018).

Skin tolerance data from human patch tests are good, while hair and scalp performance data are absent.

Side effects and safety

Irritation and allergy rates were low in the 105-patient study, and we found few allergy reports.

Bottom line

One of the better evidence-backed mild cleansers for sensitive scalps and for dry, curly hair. Expect lighter lather and gentler cleansing than a sulfate shampoo. No head-to-head scalp or hair-feel trials were found.

Studies 3

Corazza M et al. Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients. Dermatitis. 2010

Design
other
People
105
Who
Italian patients patch-tested

Tested: eight cleansing surfactants

Result: None caused irritation at the tested dilution; best tolerated were sodium cocoyl glutamate, sodium lauroyl oat amino acids and disodium cocoamphodiacetate.

Read the study ↗

Lee CH, Kawasaki Y, Maibach HI. Effect of surfactant mixtures on irritant contact dermatitis potential in man: sodium lauroyl glutamate and sodium lauryl sulphate. Contact Dermatitis. 1994

Design
rct
People
15
Who
healthy volunteers, randomized skin sites

Tested: sodium lauroyl glutamate, SLS, and mixtures

Result: Sodium lauroyl glutamate was much less irritating than SLS, and mixing it into SLS reduced SLS irritation.

Read the study ↗

Cornwell PA. A review of shampoo surfactant technology: consumer benefits, raw materials and recent developments. Int J Cosmet Sci. 2018

Design
review

Result: Overview of shampoo surfactant raw materials, consumer benefits and trends in sulfate-free systems.

Read the study ↗