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Encyclopedia

Every molecule that touches your hair

From proven medicines to kitchen-cupboard oils, with the studies behind each one.

26 entries

A

  • other

    Alcohol denat.

    Ordinary ethanol made undrinkable, a fast-drying solvent in hair sprays and gels that is not the same as the fatty alcohols in conditioners.

  • botanical

    Aloe vera

    Aloe gel is a soothing, water-binding scalp and hair conditioner, with no solid human trial showing it grows hair.

C

  • anti dandruff

    Ciclopirox

    An antifungal shampoo ingredient with randomized-trial support for scalp seborrheic dermatitis and a particular edge on itch, with no good evidence that it grows hair.

  • anti dandruff

    Climbazole

    A cosmetic azole antifungal used mostly as a booster next to zinc pyrithione or piroctone olamine, with thin evidence on its own.

  • anti dandruff

    Coal tar

    One of the oldest dandruff and psoriasis treatments; it works, but it contains carcinogens, smells, stains and is no longer anyone's first choice.

  • surfactant

    Cocamide MEA and cocamide DEA

    Foam boosters and thickeners in shampoo; the DEA type raises nitrosamine and allergy questions, which is why many brands moved to MEA or other thickeners.

  • surfactant

    Cocamidopropyl betaine

    The most common helper surfactant in shampoo, which makes sulfate cleansers gentler, thicker and foamier, and a rare cause of scalp allergy that usually comes from manufacturing impurities.

  • surfactant

    Coco-glucoside

    A coconut-derived mild cleanser that is a staple of sulfate-free shampoos, with the same contact-allergy caveat as decyl glucoside.

D

  • surfactant

    Decyl glucoside

    A plant-derived mild cleanser marketed as ultra-gentle, but its best-documented concern is a rising rate of contact allergy.

  • surfactant

    Disodium laureth sulfosuccinate

    A mild anionic cleanser often used as a secondary or co-primary surfactant that helps blends stay gentle while still cleaning.

G

  • protein or peptide

    GHK-Cu (copper tripeptide-1)

    GHK-Cu is a copper-binding peptide with a long skin-repair record but no published controlled trial for hair growth.

K

  • anti dandruff

    Ketoconazole

    An antifungal shampoo ingredient that is among the best-proven treatments for dandruff and, with much weaker evidence, a possible add-on for pattern hair loss.

L

  • surfactant

    Lauryl glucoside

    A 12-carbon alkyl glucoside that foams a little better than decyl glucoside and carries the same class contact-allergy profile.

P

  • botanical

    Peppermint oil

    In a 2014 mouse study 3% peppermint oil grew more hair than 3% minoxidil, but no human trial of peppermint oil for hair has been found.

  • anti dandruff

    Piroctone olamine

    A gentle anti-dandruff ingredient common in European shampoos, with trial results roughly equal to zinc pyrithione but mostly from manufacturers.

S

  • anti dandruff

    Salicylic acid

    A scale-loosening ingredient that helps thick flakes and scalp psoriasis plaques and works best paired with an antifungal.

  • anti dandruff

    Selenium sulfide

    An old, inexpensive anti-dandruff active that new trials suggest works about as well as ketoconazole and has been tested across all curl types.

  • surfactant

    Sodium cocoamphoacetate

    A mild two-charge helper surfactant used in baby, sulfate-free and sensitive-scalp shampoos to soften harsher cleansers.

  • surfactant

    Sodium cocoyl glutamate

    An amino-acid-based cleanser that was among the best-tolerated surfactants in a 105-patient patch-test study, with no scalp or hair trials yet.

  • surfactant

    Sodium cocoyl glycinate

    A glycine-based mild cleanser with one industry body-wash study showing mildness and no scalp or hair studies.

  • surfactant

    Sodium cocoyl isethionate

    A mild anionic cleanser, the basis of many syndet bars, with good lab evidence of being gentle on the skin barrier and growing use in sulfate-free shampoos and shampoo bars.

  • surfactant

    Sodium lauroamphoacetate

    The lauric-chain version of the amphoacetate family, used as a mild helper surfactant in sulfate-free shampoos.

  • surfactant

    Sodium lauroyl methyl isethionate

    A more soluble cousin of sodium cocoyl isethionate used as a mild cleanser in modern sulfate-free shampoos, with no independent studies of its own.

  • surfactant

    Sodium lauryl sulfate

    A cheap, strong cleanser and foamer that removes oil very well but is the most irritating common shampoo surfactant, so dermatologists use it as their standard test irritant.

T

  • botanical

    Tea tree oil

    A popular natural dandruff remedy with modest evidence, whose oxidised oil is a well-documented contact allergen.

Z

  • anti dandruff

    Zinc pyrithione

    The most widely used anti-dandruff shampoo ingredient, proven in large trials to cut flaking, though most of those trials were run by the companies that sell it.