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Encyclopedia · surfactant

Lauryl glucoside

A 12-carbon alkyl glucoside that foams a little better than decyl glucoside and carries the same class contact-allergy profile.

Cosmetic ingredient Cost $ Safety: minor

drynessitchy scalpdry scalp

What it is

Lauryl glucoside has a 12-carbon tail and is used as a primary or booster surfactant in sulfate-free and baby shampoos and cleansers, and as an emulsifier.

How it works

It forms non-ionic micelles like the other glucosides, and the longer tail gives better foam and cleaning than decyl glucoside.

What the studies show

  • In a 19-year patch-test cohort of 11,842 people, 30 reacted to alkyl glucosides, with shampoos among the commonest causal products (Gijbels 2014).
  • Patch testing with several glucosides is advised because cross-reaction between them is not automatic (Alfalah 2017).
  • A 2026 review compiles reports of allergic contact dermatitis to alkyl glucosides including lauryl glucoside (de Groot 2026).

We found no hair-specific data, so the direct evidence is weak.

Bottom line

The same advice applies as for decyl glucoside: reasonable for dry or sensitive scalps without a known allergy, and best avoided if you have reacted to glucosides.

Studies 3

Gijbels D et al. Allergic contact dermatitis caused by alkyl glucosides. 2014

Design
case series
People
11,842
Duration
19 years
Who
patients patch-tested, 30 positive to alkyl glucosides

Result: Causal products were shampoos (12), skin cleansers (12), sunscreens (5) and skin-care products (4); 16 patients had multiple contact allergies.

Read the study ↗

Alfalah M et al. Alkyl Glucosides. 2017

Design
review

Result: Alkyl glucosides were assumed low in irritancy and allergenicity, but cases of allergic contact dermatitis have accumulated since the early 2000s; sensitisation to decyl glucoside is rising in North American data; cross-reactions are common but not automatic.

Read the study ↗

de Groot AC. Contact Allergy to Alkyl Glucosides: A Review-Part 1. 2026

Design
review

Result: Alkyl glucosides (mainly decyl, lauryl, cetearyl and coco-glucoside) have low irritation potential but can induce contact sensitisation.

Read the study ↗