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Encyclopedia

Every molecule that touches your hair

From proven medicines to kitchen-cupboard oils, with the studies behind each one.

10 entries

A

  • growth stimulant

    Adenosine (topical)

    Adenosine, a natural signalling molecule, is the cosmetic hair active with the cleanest small placebo-controlled trials, mainly making thin hairs thicker.

C

  • antiandrogen

    Clascoterone

    A topical androgen blocker already approved as an acne cream whose 5% scalp solution reported positive phase 3 results in men; it is not yet approved for hair.

D

  • antiandrogen

    Dutasteride

    A stronger cousin of finasteride that blocks both forms of the DHT-making enzyme and grew more hair than finasteride in head-to-head trials.

F

  • antiandrogen

    Finasteride

    A prescription pill (and in some countries a scalp spray) that lowers DHT and is the best-proven drug for stopping male pattern hair loss.

  • antiandrogen

    Fluridil

    A topical antiandrogen designed to break down in the skin; its only human evidence is one small 2002 trial by its inventors.

G

  • antiandrogen

    GT20029

    A topical drug that tags the androgen receptor for destruction instead of just blocking it; a 12-week phase 2 in Chinese men showed modest gains.

M

  • growth stimulant

    Minoxidil

    The most widely used hair-growth treatment, available as a cheap over-the-counter lotion or foam and as a prescription tablet, with a mechanism that is still only partly understood.

P

  • antiandrogen

    Pyrilutamide

    A topical androgen blocker from the Chinese company Kintor that reported positive pivotal results in China; no peer-reviewed efficacy paper yet.

R

  • botanical

    Rosemary oil

    Rosemary oil became the internet's "natural minoxidil" from one small 2015 trial that had no placebo group and has never been replicated.

  • antiandrogen

    RU58841

    A topical androgen blocker from the 1990s that grew hair in animal and graft models but has no human efficacy trial and is sold online as a research chemical.