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Encyclopedia · supplement

Vitamin D

Hair loss goes with low vitamin D and the receptor is needed for the hair cycle, but no good trial shows supplements regrow hair if you are not deficient.

Supplement Cost $ Safety: minor

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What it is

A fat-soluble vitamin made in skin from sunlight and obtained from oily fish, egg yolk, fortified foods and supplements. The blood marker is 25-hydroxyvitamin D. Supplements come as D3 or D2; 40 IU equals 1 microgram.

How it works

The strongest hair-specific evidence is genetic. In children with hereditary vitamin D-resistant rickets, a rare disease of the vitamin D receptor, those whose receptor is absent or cannot bind DNA lose their hair, while those whose receptor merely binds the hormone poorly keep it. Hair cycling appears to depend on the receptor working even without the active hormone. That supports a role for the receptor, not that extra vitamin D boosts growth. Malloy 2011

What the studies show

  • A meta-analysis of 23 studies (3,374 patients, 7,296 controls) found lower vitamin D in non-scarring alopecia (about -7.3 ng/mL) and higher odds of deficiency (OR 3.11), with very high heterogeneity. Chen 2024
  • A meta-analysis by alopecia type found deficiency in about 47-54% of patients with alopecia areata, female and male pattern loss and telogen effluvium. Levels were significantly lower than controls only in alopecia areata and female pattern loss; for male pattern loss the deficiency odds were not significant. Yongpisarn 2024
  • A 2026 meta-analysis of 29 studies found lower vitamin D (standardized mean difference -0.87) and ferritin in telogen effluvium, with high heterogeneity. Ahmed 2026
  • In 90 women with chronic telogen effluvium versus 90 controls, vitamin D, ferritin and B12 did not differ, but zinc was lower. Durusu Turkoglu 2024
  • A systematic review of supplements in people without known deficiency graded vitamin D3 trials as low-quality evidence for benefit. Drake 2023

These are association studies. Low vitamin D could be a cause, a consequence of indoor life, illness or obesity, or a bystander. No placebo-controlled hair trial in non-deficient adults turned up.

How it's used in studies

Hair-specific supplementation trials are few and small, mostly in alopecia areata or in combination products, so no hair dose is established. For safety context, the European Food Safety Authority upper limit for adults is 100 micrograms (4,000 IU) a day.

Side effects and safety

Excess raises blood calcium (nausea, kidney stones, kidney injury) and is rarely a problem below the upper limit. Dose to a measured level, not to a hair goal. High-dose prescriptions exist for deficiency.

Bottom line

Worth a blood test if you have unexplained shedding or live with little sun, and worth correcting a confirmed deficiency. With a normal level, extra vitamin D is not a proven hair treatment and does not replace minoxidil or a DHT blocker for pattern loss. Discuss with a doctor.

Fun facts

  • A rare receptor mutation can cause total hair loss in infants even when blood vitamin D is high, because the follicle needs the receptor itself. Malloy 2011

Studies 6

Malloy PJ et al. The role of vitamin D receptor mutations in the development of alopecia. 2011

Design
review
Who
hereditary vitamin D-resistant rickets

Result: Children with an absent or non-DNA-binding vitamin D receptor lose their hair; hair cycling depends on the receptor even without the active hormone.

Read the study ↗

Chen Y et al. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis. 2024

Design
meta analysis
Who
3,374 patients and 7,296 controls (23 studies)

Result: Lower 25(OH)D (about -7.3 ng/mL) and higher odds of deficiency (OR 3.11) in non-scarring alopecia; very high heterogeneity.

Read the study ↗

Yongpisarn T et al. Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis. 2024

Design
meta analysis
Who
patients with alopecia areata, pattern loss and telogen effluvium

Result: Deficiency in about 47-54% of patients; lower levels than controls only in alopecia areata and female pattern loss.

Read the study ↗

Ahmed A et al. Association between Serum Trace Elements and Telogen Effluvium: A Systematic Review and Meta-Analysis. 2026

Design
meta analysis
Who
people with telogen effluvium vs controls (29 studies)

Result: Lower vitamin D (SMD -0.87) and lower ferritin (SMD -0.57) in telogen effluvium, with high heterogeneity.

Read the study ↗

Durusu Turkoglu IN et al. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels. 2024

Design
case control
People
180
Who
90 women with chronic telogen effluvium vs 90 controls

Result: Only zinc (lower) and selenium (higher) differed; ferritin, B12, vitamin D, biotin and hemoglobin did not.

Read the study ↗

Drake L et al. Nutritional supplements for hair loss: a systematic review. JAMA Dermatol. 2023

Design
systematic review
People
30
Who
30 studies of supplements for hair loss

Tested: oral supplements including apple nutraceutical and capsaicin-isoflavone

Result: Apple nutraceutical and capsaicin-isoflavone were among the supplements with higher-quality evidence; adverse effects were rare and mild.

Read the study ↗