Encyclopedia · supplement
Omega-3 fatty acids
Fish-oil fats whose only hair evidence is a branded omega-3/6 plus antioxidant product tested in women.
What it is
Omega-3 fats (EPA and DHA) come from oily fish, algae and fish-oil capsules. Omega-6 fats come from plant oils.
How it works
They are anti-inflammatory building blocks of cell membranes. Which ingredient might matter for follicles is not known.
What the studies show
- In a 6-month comparison of 120 women with hair loss, a product with omega 3 and 6 plus antioxidants gave better photo-assessed density, a lower telogen percentage and more thick anagen hairs than the control group. About 87-90% of treated women reported benefit. The control was not described as placebo in the abstract, and the study was manufacturer-linked. Le Floc'h 2015
- A systematic review of 30 studies listed omega 3 and 6 with antioxidants among the supplements with the highest-quality evidence of benefit, with rare mild side effects. Drake 2023
- A network meta-analysis found supplements overall improved hair density and blinded doctor ratings and were well tolerated, but large high-quality trials are still needed. Zhou 2026
It is not known which ingredient drove the effect, and there is no independent replication.
Side effects and safety
Fish oil can cause fishy reflux and loose stools and, at high doses, slightly raises bleeding tendency. The European Food Safety Authority found too little data to set an upper limit for EPA and DHA. Check with a doctor if you take blood thinners.
Bottom line
Limited evidence for the tested branded combination and weak evidence for plain fish oil. Eating oily fish twice a week fits general health advice, but do not expect regrowth from capsules and do not use them instead of minoxidil or a DHT blocker for pattern loss. Discuss with a doctor.
Studies 3
Le Floc'h C et al. Effect of a nutritional supplement on hair loss in women. 2015
Tested: omega 3 and 6 plus antioxidants vs control
Result: Better photo-assessed density, lower telogen percentage and more thick anagen hairs; control not described as placebo; manufacturer-linked.
Read the study ↗Drake L et al. Nutritional supplements for hair loss: a systematic review. JAMA Dermatol. 2023
Tested: oral supplements including apple nutraceutical and capsaicin-isoflavone
Result: Apple nutraceutical and capsaicin-isoflavone were among the supplements with higher-quality evidence; adverse effects were rare and mild.
Read the study ↗Zhou L et al. Dietary supplements in androgenetic alopecia: systematic review and network meta-analysis. Front Nutr. 2026
Tested: dietary supplements vs placebo or conventional treatments
Result: Saw palmetto extract scored better than placebo or conventional treatments on blinded doctor assessment and pumpkin seed oil improved density vs placebo; low-certainty, heterogeneous.
Read the study ↗