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Encyclopedia · protein or peptide

Biotinoyl tripeptide-1

Biotinoyl tripeptide-1 is biotin attached to the GHK peptide; the only hair-growth data are manufacturer claims.

Cosmetic ingredient Cost $$

thinninghair loss

What it is

Biotinoyl tripeptide-1 is the GHK peptide (see GHK-Cu) chemically linked to biotin. It is the peptide part of the supplier blend Procapil, which also contains oleanolic acid from olive and apigenin. It is a cosmetic ingredient.

How it works

The supplier says it strengthens the anchoring of the hair root. This is a marketing claim, and no peer-reviewed paper confirming it was found.

What the studies show

  • A search of the medical literature for biotinoyl tripeptide-1 or biotinyl-GHK with hair terms found no study of this molecule.
  • The supplier's material describes a 4-month placebo-controlled study of the Procapil blend in women with early female pattern loss, but the full documents could not be checked, and as sponsor material on a blend it cannot isolate this peptide.

How it's used in studies

The supplier recommends a 3% level for the blend (manufacturer data).

Side effects and safety

No problems have been reported, but there are no data. Biotin taken by mouth can distort some lab tests; topical use is not known to.

Bottom line

Marketing claims only. It is possibly harmless and possibly useless. Spend money on proven treatments first.

Studies 0

No studies are listed for this page yet.